参苓山蛸汤联合隔姜灸治疗脾胃虚弱型浅表性胃炎患者的效果.pdf
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1、110 2023 年 8 月中国民康医学Aug.,2023第35卷 半月刊 第15期摇 摇 摇 摇 摇 Medical Journal of Chinese Peoples Health Vol.35 Semimonthly No.15揖中医药研究铱参苓山蛸汤联合隔姜灸治疗脾胃虚弱型浅表性胃炎患者的效果周莺歌(滑县人民医院中医内科,河南 安阳 456400)【摘要】目的:观察参苓山蛸汤联合隔姜灸治疗脾胃虚弱型浅表性胃炎患者的效果。方法:选取 2020 年 10 月至 2022 年 10 月该院收治的 66 例脾胃虚弱型浅表性胃炎患者进行前瞻性研究,按随机数字表法将其分为对照组与观察组各 33
2、例。对照组采用隔姜灸治疗,观察组在对照组基础上联合参苓山蛸汤治疗,比较两组临床疗效、治疗前后中医证候积分、胃肠激素指标(胃泌素、胃动素)水平、炎性因子 白细胞介素-6(IL-6)、肿瘤坏死因子-(TNF-)、表皮生长因子(EGF)、6-酮-前列腺素(6-keto-PGF1)水平和不良反应发生率。结果:观察组治疗总有效率为 93.94%(31/33),高于对照组的 75.76%(25/33),差异有统计学意义(P0.05);治疗后,两组食后腹胀、大便溏稀、胃脘痛、发酸嗳气等中医证候积分均低于治疗前,且观察组低于对照组,差异有统计学意义(P0.05);两组胃泌素水平均低于治疗前,且观察组低于对照组
3、,两组胃动素水平均高于治疗前,且观察组高于对照组,差异有统计学意义(P0.05);治疗后,两组 IL-6、TNF-水平均低于治疗前,且观察组低于对照组,两组 EGF、6-keto-PGF1 水平均高于治疗前,且观察组高于对照组,差异有统计学意义(P0.05)。结论:参苓山蛸汤联合隔姜灸治疗脾胃虚弱型浅表性胃炎患者可提高治疗总有效率,降低中医证候积分,改善胃肠激素指标和炎性因子水平,其效果优于单纯隔姜灸治疗。【关键词】参苓山蛸汤;隔姜灸;脾胃虚弱型;浅表性胃炎;炎性因子;胃肠激素;中医证候积分doi:10.3969/j.issn.1672-0369.2023.15.033中图分类号:R573.3
4、 文献标识码:B 文章编号:1672-0369(2023)15-0110-04Effects of Shenling Shanxiao decoction combined with ginger moxibustion in treatment of patients with superficial gastritis of spleen and stomach deficiency typeZHOU Yingge(Department of Internal Medicine of TCM of Hua County Peoples Hospital,Anyang 456400 Hena
5、n,China)【Abstract】Objective:To observe effects of Shenling Shanxiao decoction combined with ginger moxibustion in treatment of patients with superficial gastritis of spleen and stomach deficiency type.Methods:A prospective study was conducted on 66 patients with superficial gastritis of spleen and s
6、tomach deficiency type admitted to this hospital from October 2020 to October 2022.They were divided into control group and observation group according to the random number table method,33 cases in each.The control group was treated with ginger moxibustion,while the observation group was treated wit
7、h Shenling Shanxiao decoction on the basis of that of the control group.The clinical efficacy,the TCM syndrome scores,the gastrointestinal hormone index levels(gastrin,motilin),the inflammatory factors interleukin-6(IL-6),tumor necrosis factor-(TNF-),epidermal growth factor(EGF),6-keto-prostaglandin
8、(6-keto-PGF1)levels before and after the treatment,and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of treatment in the observation group was 93.94%(31/33),which was higher than 75.76%(25/33)in the control group,and the difference was stati
9、stically significant(P0.05).After the treatment,the scores of TCM syndromes such as abdominal distension,loose stool,epigastric pain,acid and belching in the two groups were lower than those before the treatment,those in the observation group were lower than those in the control group,and the differ
10、ences were statistically significant(P0.05).The levels of gastrin in the two groups were lower than those before the treatment,and that in the observation group was lower than that in the control group;the levels of motilin in the two groups were higher than those before the treatment,and that in th
11、e observation group was higher than that in the control group;and the differences were statistically significant(P0.05).After the treatment,the levels of serum IL-6 and TNF-in the two groups were lower than those before the treatment,and those in the observation group were lower than those in the co
12、ntrol group;the levels of EGF and 6-keto-PGF1 in the two groups were higher than those before the treatment,and those in the observation group were higher than those in the control group;and the differences were statistically significant(P0.05).Conclusions:Shenling Shanxiao decoction combined with g
13、inger moxibustion can improve the total effective rate of treatment,reduce the scores of TCM syndromes,and improve the levels of intestinal hormone indexes and inflammatory factors in the patients with superficial gastritis of spleen and stomach deficiency type.Moreover,it is superior to single ging
14、er moxibustion treatment.【Keywords】Shenling Shanxiao decoction;Ginger moxibustion;Spleen and stomach deficiency type;Superficial gastritis;Inflammatory factor;Gastrointestinal hormone;TCM syndrome score收稿日期:2023-05-04作者简介:周莺歌(1976.02),女,汉族,河南滑县人,本科,副主任中医师,研究方向为中医内科。111 2023 年 8 月中国民康医学Aug.,2023第35卷
15、半月刊 第15期摇 摇 摇 摇 摇 Medical Journal of Chinese Peoples Health Vol.35 Semimonthly No.15仁、党参、山药各 20g,茯苓、陈皮各 10g,甘草6g。随症加减:严重腹胀加木香 6g;严重痞满加焦山楂 6g;严重四肢冰凉加干姜 6g。加水 600mL煎煮至 150mL,分 3 次温服,1 剂/d。两组均连续治疗 4 周。1.3 观察指标(1)比较两组临床疗效8。显效:胃脘痛、胃胀等临床症状显著好转,中医证候积分降低 90%;有效:胃脘痛、胃胀等临床症状有所好转,中医证候积分降低 60%90%;无效:未达以上标准。总有效率
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- 参苓山蛸汤 联合 隔姜灸 治疗 脾胃 虚弱 浅表性 胃炎 患者 效果
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