复旦大学科研论文写作方法试题.docx

复旦大学科研论文写作方法试题
1. 修改意见：
1）题目不够确切，没有明确的点明本文的论述重点。本文讲述的是运动在rats局灶性脑缺血后改善运动功能方面的机制，而本文的标题不够确切。
2）语言不够精炼，比如The results showed that exercise improved recovery of motor function of rats after MCAO. Meanwhile, exercise also increased BDNF and VEGF, and reduced Nogo-A in ischemic brain.（在此只是这两句话的修改）
可修改后为：The results showed that exercise improved recovery of motor function, increased BDNF and VEGF, and reduced Nogo-A in ischemic brain of rats after MCAO.
3）实验设计方面：
①实验材料的选择方面，rats的选入及排出标准不够明确，rats的种属、窝别、性别、年龄、体重等方面在实验设计中没有明确介绍。
②Rats的样本数量太少
③没有说明运用何种统计检验方法
4）Figure3可以添加相对应的MCAO后1 3周未运动的rats的神经元投射情况。
5）排版有点小问题，可以把Figures and Legends插入到Results相对应的部位。放到的最后的话不方便阅读者寻找和查看。
6）缺少关键词
7）缺少参考文献
8）图片比例等方面欠恰当、字迹太小不方便阅读（特别是Figure5），Figure1没有总标题，还有些图片的解释不是很详细

2．修改题目及摘要
1）原文题目：Exercise promotes axon regeneration of projection neurons in rats
改为：The mechanism of exercise to improve recovery of motor function of rats after MCAO
2）原文摘要：
Abstract
Rats were subjected to a transient MCAO to induce focal cerebral ischemic injury, followed by 30 minutes of exercise training daily for 5 to 28 days after MCAO. Motor function was tested using the rotarod test. We used fluorogold (FG) nigral injection to trace striatonigral and corticonigral projection neurons, and green fluorescent protein (GFP)-targeting retroviral vectors combined with FG double labeling (GFP+ -FG+) to detect newborn projection neurons. The results showed that exercise improved recovery of motor function of rats after MCAO. Meanwhile, exercise also increased BDNF and VEGF, and reduced Nogo-A in ischemic brain. With this condition, we further found that exercise significantly increased the number of GFP+ -FG+ neurons in the striatum and cortex ipsilateral to MCAO, suggesting an increase of newborn striatonigral and corticonigral projection neurons by exercisepost-stroke. In addition, we found that exercise also increased NeuN or FG immunopositive staining cells in the striatum and cortex, the ischemic territory, andtyrosine hydroxylase immunopositive staining cells in the substantia nigra, a region remote from the ischemic territory.
修改摘要：主要是添加了一定的相关知识和结论、并对原文摘要的某些句子进行了精炼。
修改后摘要：
Abstract
There is growing recognition that exercise plays an important role in improving neurological outcomes after focal cerebral ischemia. The present study was designed to elucidate the exact molecular and cellular mechanisms of exercise to improve recovery of motor function and rats were subjected to a transient MCAO to induce focal cerebral ischemic injury, followed by 30 minutes of exercise training daily for 5 to 28 days after MCAO. Motor function was tested using the rotarod test. We used fluorogold (FG) nigral injection to trace striatonigral and corticonigral projection neurons, and green fluorescent protein (GFP)-targeting retroviral vectors combined with FG double labeling (GFP+ -FG+) to detect newborn projection neurons. The results showed that exercise improved recovery of motor function, increased BDNF and VEGF, and reduced Nogo-A in ischemic brain of rats after MCAO. With this condition, we further found that exercise significantly increased the number of GFP+ -FG+ neurons in the striatum and cortex ipsilateral to MCAO, suggesting an increase of newborn striatonigral and corticonigral projection neurons by exercisepost-stroke. In addition, we found that exercise also increased NeuN or FG immunopositive staining cells in the striatum and cortex, the ischemic territory, andtyrosine hydroxylase immunopositive staining cells in the substantia nigra, a region remote from the ischemic territory. The results suggest that reconstruction of new neural networks within the nuclei have important roles in function repair of adult brain, and that exercise may be valuable for morphological and functional repairs in the injured adult mammalian brains.